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Meeting Report: Epithelial Morphogenesis and Diseases

The meeting was organized in sections covering stem cells, epithelial morphogenesis, cell-cell adhesin, epithelial polarity and - ultimately - epithelial diseases and cancer. 

The Pathological Society Lecture was given by Professor Margaret Frame (Edinburgh, UK) in the Epithelial Cancer session.  She presented studies of the role of tyrosine kinase Src and its substrate, focal adhesion kinase (FAK) in promoting cancer invasion and metastasis by perturbing cancer cell-cell contacts and integrin-dependent cell-matrix adhesion.

Professor Frame demonstrated an interesting in vivo model of genetically engineered mouse with cancer, with ‘in-built’ fluorescence, being used for novel intra-vital imaging technologies. Using this model allows investigators to test novel agents with anti-invasive or anti-metastatic potential.

The meeting was held in the beautiful campus of the University of Greenwich. Conference room, hotel accommodation and food service areas were close together and convenient.  A friendly atmosphere allowed for productive discussions throughout the day and during recreational time.

Vania Braga,
National Heart and Lung Institute
Imperial College London

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